Autoantigen-specific memory CD4+ T cells are prevalent early in progression to Type 1 diabetes

Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health

Sefina Arif, Timothy Tree, Thomas P. Astill et al. · Journal of Clinical Investigation · 2004 · 479 citations · Full text

Life Sciences, Endocrinology, Immunology +17

Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope

Sally C. Kent, Yahua Chen, Lisa Bregoli et al. · Nature · 2005 · 413 citations

Life Sciences, Endocrinology, Immunology +14

Autoreactive T Cells in Healthy Individuals

Nancy A. Danke, David M. Koelle, Cassian Yee et al. · The Journal of Immunology · 2004 · 381 citations · Full text

Life Sciences, Cell Biology, Immunology +15

Nasal insulin to prevent type 1 diabetes in children with HLA genotypes and autoantibodies conferring increased risk of disease: a double-blind, randomised controlled trial

Kirsti Näntö‐Salonen, Antti Kupila, Satu Simell et al. · The Lancet · 2008 · 379 citations

Medicine, Immunology, Pediatrics +13

Combined Analysis of Autoantibodies Improves Prediction of IDDM in Islet Cell Antibody-Positive Relatives

Polly J. Bingley, Michael R. Christie, Ezio Bonifacio et al. · Diabetes · 1994 · 371 citations · Full text

Life Sciences, Endocrinology, Immunology +12