Genetic polymorphisms of manganese superoxide dismutase, NAD(P)H:quinone oxidoreductase, glutathione S-transferase M1 and T1, and the susceptibility to drug-induced liver injury

Causality assessment of adverse reactions to drugs—I. A novel method based on the conclusions of international consensus meetings: Application to drug-induced liver injuries

Gaby Danan, C Bénichou · Journal of Clinical Epidemiology · 1993 · 1.5K citations

Medicine, Pharmacology, Pharmacovigilance +12

Genetic Risk and Carcinogen Exposure: a Common Inherited Defect of the Carcinogen-Metabolism Gene Glutathione S-Transferase M1 (GSTM1) That Increases Susceptibility to Bladder Cancer

Douglas A. Bell, Jack A. Taylor, David F. Paulson et al. · JNCI Journal of the National Cancer Institute · 1993 · 705 citations

Medicine, Genetics, Urology +17

Structural Dimorphism in the Mitochondrial Targeting Sequence in the Human Manganese Superoxide Dismutase Gene

Satoe Shimoda‐Matsubayashi, Hiroto Matsumine, Tomonori Kobayashi et al. · Biochemical and Biophysical Research Communications · 1996 · 499 citations

Life Sciences, Genetics, Molecular Biology +12

Polymorphism of the N -acetyltransferase 2 gene as a susceptibility risk factor for antituberculosis drug-induced hepatitis

Yi‐Shin Huang, Herng‐Der Chern, Wei‐Juin Su et al. · Hepatology · 2002 · 433 citations

Medicine, Molecular Genetics, Pharmacology +10

Cytochrome P450 2E1 Genotype and the Susceptibility to Antituberculosis Drug–Induced Hepatitis

Yi‐Shin Huang, Herng‐Der Chern, Wei‐Juin Su et al. · Hepatology · 2003 · 427 citations · Full text

Medicine, Pharmacology, Toxicology +15