Concepedia
Bioorganic & Medicinal Chemistry Letters · 1999 · 78 citations · 10 references
Molecular PharmacologyMedicinal ChemistryBiochemistryMedicineNatural SciencesBioconjugationPeptide SynthesisDrug DevelopmentChemical BiologyPharmacologyPharmaceutical ChemistryDrug Discovery
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Partial denaturation of transthyretin is sufficient for amyloid fibril formation in vitro
Wilfredo Colón, Jeffery W. Kelly · Biochemistry · 1992 · 570 citations
The Acid-Mediated Denaturation Pathway of Transthyretin Yields a Conformational Intermediate That Can Self-Assemble into Amyloid
Zhihong Lai, Wilfredo Colón, Jeffery W. Kelly · Biochemistry · 1996 · 562 citations
Synchrotron X-ray studies suggest that the core of the transthyretin amyloid fibril is a continuous β-sheet helix
Colin Blake, Louise C. Serpell · Structure · 1996 · 373 citations · Full text
Protein Chemistry, Protein Function, Protein Assembly +12
Palladium-Catalyzed Amination of Aryl Halides: Mechanism and Rational Catalyst Design
John F. Hartwig · Synlett · 1997 · 295 citations
Tin-free Amide Sources, Chemical Engineering, Cross-coupling Reaction +10
Transthyretin mutation Leu-55-Pro significantly alters tetramer stability and increases amyloidogenicity
Sandra L. McCutchen, Wilfredo Colón, Jeffery W. Kelly · Biochemistry · 1993 · 199 citations