Teratogenic valproic acid concentrations: Infusion by implanted minipumps vs conventional injection regimen in the mouse

Valproic acid and its metabolites: placental transfer, neonatal pharmacokinetics, transfer via mother's milk and clinical status in neonates of epileptic mothers.

Heinz Nau, D. Rating, S. Koch et al. · Journal of Pharmacology and Experimental Therapeutics · 1981 · 231 citations

Medicine, Pharmacokinetics, Pharmacology +17

A new model for embryotoxicity testing: teratogenicity and pharmacokinetics of valproic acid following constant-rate administration in the mouse using human therapeutic drug and metabolite concentrations

Heinz Nau, Rainer Zierer, Horst Spielmann et al. · Life Sciences · 1981 · 169 citations

Pharmacy, Pharmacokinetics, Toxicology +17

Teratogenicity of valproic acid: In vivo and in vitro investigations

John Y. Kao, Nigel A. Brown, Eugenia H. Goulding et al. · Teratogenesis Carcinogenesis and Mutagenesis · 1981 · 163 citations

Life Sciences, Developmental Biology, Pharmacology +17

Valproic acid dosage and plasma protein binding and clearance

Andrew Bowdle, Indravadan H. Patel, René H. Levy et al. · Clinical Pharmacology & Therapeutics · 1980 · 147 citations

Pharmacy, Clinical Pharmacokinetics, Pharmacology +17

Valproic Acid and Metabolites: Pharmacological and Toxicological Studies

Heinz Nau, Wolfgang Löscher · Epilepsia · 1984 · 144 citations

Medicine, Pharmacology, Pharmacotherapy +14