Journal of the American Chemical Society · 2011 · 252 citations · 58 references
Life SciencesGeneticsMolecular BiologySynthetic BiologyGenetic CodeProtein SynthesisAmino AcidsC. Elegans Developmental ModelsExpanded Genetic CodesGenetic Code ExpansionNematode Developmental BiologyNematode GenomicsSynthetic Genetic CodeUnnatural Amino Acid Incorporation
Genetic code expansion, for the site-specific incorporation of unnatural amino acids into proteins, is currently limited to cultured cells and unicellular organisms. Here we expand the genetic code of a multicellular animal, the nematode Caenorhabditis elegans.
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Creation of Low-Copy Integrated Transgenic Lines in <i>Caenorhabditis elegans</i>
Vida Praitis, Elizabeth Casey, David C. Collar et al. · Genetics · 2001 · 831 citations