Present Position of Immunization Against Poliomyelitis with Live Virus Vaccines

Abstract

Immunization against poliomyelitis with orally administered live attenuated poliovirus vaccine presents special problems not previously encountered with other live virus vaccines employed in human beings, and it is entirely proper to approach it in the most cautious and critical manner. The recent communications (Dick and Dane, 1958; Dane et al., 1958; Clarke et al., 1958) and editorial comments (leading article, 1958) in the British Medical Journal did not take into account all the available published and unpublished data that were available to the writers, and, in my opinion, did not give a complete picture of the present status of our knowledge on this subject.