Curcumin reduces the expression of Bcl-2 by upregulating miR-15a and miR-16 in MCF-7 cells

The Release of Cytochrome c from Mitochondria: A Primary Site for Bcl-2 Regulation of Apoptosis

Ruth M. Kluck, Ella Bossy‐Wetzel, Douglas R. Green et al. · Science · 1997 · 4.7K citations

Life Sciences, Biochemistry, Cell Biology +17

<i>miR-15</i> and <i>miR-16</i> induce apoptosis by targeting BCL2

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Molecular mechanisms of curcumin-induced cytotoxicity: induction of apoptosis through generation of reactive oxygen species, down-regulation of Bcl-XL and IAP, the release of cytochrome c and inhibition of Akt

Ju-Hyung Woo, Young Ho Kim, Yun‐Jung Choi et al. · Carcinogenesis · 2003 · 443 citations · Full text

Life Sciences, Oncology, Pharmacology +17

Curcumin (diferuloylmethane) alters the expression profiles of microRNAs in human pancreatic cancer cells

Michael Sun, Zeev Estrov, Yuan Ji et al. · Molecular Cancer Therapeutics · 2008 · 408 citations · Full text

Medicine, Oncology, Pharmacology +17

MicroRNA gene expression during retinoic acid-induced differentiation of human acute promyelocytic leukemia

Ramiro Garzon, Flavia Pichiorri, Tiziana Palumbo et al. · Oncogene · 2007 · 362 citations

Life Sciences, Cell Biology, Molecular Biology +16