Population pharmacokinetic and pharmacodynamic modelling of artemisinin and mefloquine enantiomers in patients with falciparum malaria

Xpose—an S-PLUS based population pharmacokinetic/pharmacodynamic model building aid for NONMEM

E. Niclas Jonsson, Mats O. Karlsson · Computer Methods and Programs in Biomedicine · 1998 · 1K citations

Pharmacy, Pharmacokinetics, Pharmacology +12

Plasmodium falciparum: In Vitro Studies of the Pharmacodynamic Properties of Drugs Used for the Treatment of Severe Malaria

Nicholas J. White, PAH Holloway, Geoffrey Pasvol et al. · Experimental Parasitology · 1993 · 289 citations

Medicine, Pharmacokinetics, Pharmacology +17

RANDOMISED COMPARATIVE STUDY OF MEFLOQUINE, QINGHAOSU, AND PYRIMETHAMINE-SULFADOXINE IN PATIENTS WITH FALCIPARUM MALARIA

Guoqiao Li, Xing-Bo Guo, Keith Arnold et al. · The Lancet · 1984 · 211 citations

Pharmacy, Pharmacology, Pharmacotherapy +11

Dynamic Alteration in Splenic Function during Acute falciparum Malaria

Sornchai Looareesuwan, May Ho, Yupaporn Wattanagoon et al. · New England Journal of Medicine · 1987 · 192 citations

Veterinary Medicine, Hematology, Infectious Diseases +15

Artemisinin pharmacokinetics is time-dependent during repeated oral administration in healthy male adults.

Michael Ashton, Trinh Ngoc Hai, Nguyen Duy Sy et al. · PubMed · 1998 · 129 citations

Medicine, Pharmacokinetics, Pharmacology +15