Application of H/D Exchange to Hydrogen Bonding in Small Molecules

Tanya L. Schneider, Kevin T. Halloran, Julie A. Hillner, Rebecca R. Conry, Brian R. Linton

Chemistry - A European Journal · 2013 · 20 citations · 45 references

Concepts

Abstract

Do you recognize me? A series of simple amides has been used to demonstrate the application of hydrogen/deuterium exchange in small-molecule hydrogen bonding. By comparison with similar controls, the degree of protection from H/D exchange can provide insight into the degree of hydrogen bonding (see scheme).

References

45