Ganglion cell and inner plexiform layer thickness determined by spectral domain optical coherence tomography in patients with brain lesions

Abstract

Our results suggest that various kinds of brain lesions with different locations show considerable reduction in GCIPL thickness. Thickness of the GCIPL performed better than conventional pRNFL thickness for the diagnosis of retinal ganglion cell damage induced by brains lesions. The pattern of GCIPL loss may be of particular usefulness in recognising a potential intracranial lesion in cases suspected of having normal-tension glaucoma. GCIPL thickness determined by OCT can be an early and useful marker to estimate the status of the visual pathway in various brain lesions.