Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · 2003 · 586 citations · 24 references
MedicineBiomedical InformaticsHealth InformaticsClinical EpidemiologyPatient SafetyPharmacovigilanceDrug Safety InformaticsEvidence-based MedicinePharmacoepidemiologyPharmacovigilance Data SourcesClinical Drug DatabasesDrug Safety ReportingEpidemiologic Surveillance SystemsMedication Safety AnalysisResearch ArticlesSafety Database Review
The United Kingdom General Practice Research Database (GPRD) is an office-based, computer-generated, medical resource designed from its inception to be used for epidemiologic research. A distinct version of the GPRD is maintained by the Boston Collaborative Drug Surveillance Program and has been the source of more than 130 scientific articles primarily addressing drug safety issues. We reviewed evidence related to the validity of the GPRD. Specifically, with our extensive experience with this automated database, we evaluated the quality and completeness of the data that it contains.
24
Bernard Fisher, Joseph P. Costantino, D. Lawrence Wickerham et al. · JNCI Journal of the National Cancer Institute · 1998 · 5.5K citations · Full text
Risks of bleeding peptic ulcer associated with individual non-steroidal anti-inflammatory drugs
M. J. S. Langman, J Weil, Paul Wainwright et al. · The Lancet · 1994 · 877 citations
Risk of venous thromboembolism in users of hormone replacement therapy
Edel Daly, Martin Vessey, Michael M. Hawkins et al. · The Lancet · 1996 · 829 citations