Concepedia

Activating germline mutations in STAT3 cause early-onset multi-organ autoimmune disease

Sarah E. Flanagan, Emma Haapaniemi, Mark A. Russell, Richard Caswell, Hana Lango Allen, Elisa De Franco, Timothy J. McDonald, Hanna Rajala, Anita Ramelius, John Barton,

Nature Genetics · 2014 · 500 citations · 19 references

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19

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

Craig L. Bennett, Jacinda R. Christie, Fred Ramsdell et al. · Nature Genetics · 2001 · 3.4K citations

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Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

Jeffrey C. Barrett, David Clayton, Patrick Concannon et al. · Nature Genetics · 2009 · 1.8K citations · Full text

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STAT3 Regulates Cytokine-mediated Generation of Inflammatory Helper T Cells

Xuexian O. Yang, Athanasia D. Panopoulos, Roza Nurieva et al. · Journal of Biological Chemistry · 2007 · 1.5K citations · Full text

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An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains

Johanna Aaltonen, Petra Björses, Jaakko Perheentupa et al. · Nature Genetics · 1997 · 1.2K citations

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<i>STAT3</i> Mutations in the Hyper-IgE Syndrome

Steven M. Holland, Frank R. DeLeo, Houda Zghal Elloumi et al. · New England Journal of Medicine · 2007 · 1.2K citations · Full text

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