Post-operative circulating cytokine patterns — the influence of infection

Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells.

Jack Gauldie, Carl D. Richards, D.C. Harnish et al. · Proceedings of the National Academy of Sciences · 1987 · 1.6K citations · Full text

2/B-cell Stimulatory Factor, Immunology, Immune Regulation +25

The complex pattern of cytokines in serum from patients with meningococcal septic shock. Association between interleukin 6, interleukin 1, and fatal outcome.

Anders Waage, P Brandtzæg, Alfred Halstensen et al. · The Journal of Experimental Medicine · 1989 · 1.2K citations · Full text

Inflammation, Cytokine, Autoimmune Disease +15

Increased plasma levels of interleukin-6 in sepsis [see comments]

C. Erik Hack, ER de Groot, RJ Felt-Bersma et al. · Blood · 1989 · 810 citations · Full text

Cytokine Serum Level During Severe Sepsis in Human IL-6 as a Marker of Severity

PIERRE DAMA, Didier Ledoux, Monique Nys et al. · Annals of Surgery · 1992 · 802 citations

Inflammation, Cytokine, Human Il-6 +15

Response of Serum Interleukin-6 in Patients Undergoing Elective Surgery of Varying Severity

Anne Cruickshank, W.D. Fraser, H.J.G. Burns et al. · Clinical Science · 1990 · 758 citations