Design of biodegradable nanoparticles: a novel approach to encapsulating poorly soluble phytochemical ellagic acid

Indu Bala, V. Bhardwaj, S. Hariharan, Johannes Sitterberg, Udo Bakowsky, M. N. V. Ravi Kumar

Nanotechnology · 2005 · 70 citations · 12 references

Concepts

Abstract

Nanosizing of poorly water soluble drugs or incorporating them into nanoparticles to increase their solubility and thereby the bioavailability has become a favoured approach today. This work describes a novel method for encapsulating poorly water soluble phytochemical ellagic acid that is also sparingly soluble/insoluble in routine solvents used to prepare nanoparticles.

References

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