Discovery That Theonellasterol a Marine Sponge Sterol Is a Highly Selective FXR Antagonist That Protects against Liver Injury in Cholestasis - Concepedia

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Discovery That Theonellasterol a Marine Sponge Sterol Is a Highly Selective FXR Antagonist That Protects against Liver Injury in Cholestasis

DOI Full Paper Access

78

Citations

32

References

2012

Year

Barbara Renga, Andrea Mencarelli, Claudio D’Amore, Sabrina Cipriani, Maria Valeria D’Auria, Valentina Sepe, Maria Giovanna Chini, Maria Chiara Monti, Giuseppe Bifulco, Angela Zampella,

Abstract

FXR antagonism in vivo results in a positive modulation of MRP4 expression in the liver and is a feasible strategy to target obstructive cholestasis.

References

	Year	Citations

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