Canadian Journal of Chemistry · 1974 · 34 citations · 0 references
Natural SciencesChemistryMedicinal ChemistryOrganic ChemistrySynthetic Medicinal ChemistryAlkaloid BiosynthesisOrganic SynthesisRetrosynthetic AnalysisLactam SynthesisNatural Product SynthesisNatural Product Total SynthesisTotal Synthesis-derived Analogues
Lucidusculine 1 was converted into the lactame 5. This compound is identical with the corresponding racemate described in the accompanying Communication. The synthesis of napelline 2 from the lactame 5 is discussed. The process completes the first (formal) total synthesis of a racemic hexacyclic polysubstituted aconite alkaloid.