Reconstitution of a thymus cell‐deprived immune system by syngeneic and allogeneic thymocytes <i>in vitro</i>

Abstract

Abstract Mouse spleen cell suspensions deprived of their T cells by treatment with anti‐Θ‐serum and complement exhibit a drastically reduced immune response to sheep red blood cells in vitro . Syngeneic thymocytes generally fail to reconstitute the system. A full response can, however, be obtained by the addition of thymocytes from syngeneic mice pretreated with hydrocortisone, or by the addition of allogeneic thymocytes.