In vitro mechanism for downregulation of <scp>ER</scp> ‐α expression by epigallocatechin gallate in <scp>ER</scp> +/ <scp>PR</scp> + human breast cancer cells - Concepedia

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In vitro mechanism for downregulation of <scp>ER</scp> ‐α expression by epigallocatechin gallate in <scp>ER</scp> +/ <scp>PR</scp> + human breast cancer cells

60

Citations

48

References

2013

Year

Francesca De Amicis, Alessandra Russo, Paola Avena, Marta Santoro, Adele Vivacqua, Daniela Bonofiglio, Loredana Mauro, Saveria Aquila, Donatella Tramontano, Suzanne A.W. Fuqua,

Molecular Nutrition & Food Research

Abstract

Our data provide evidence for a mechanism by which EGCG downregulates ER-α and explains the inhibitory action of EGCG on the proliferation of ER+ PR+ cancer cells tested. We suggest that the EGCG/PR-B signaling should be further exploited for clinical approach.

References

	Year	Citations

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