Nonactin biosynthesis: Setting limits on what can be achieved with precursor-directed biosynthesis

Precursor-Directed Biosynthesis of Erythromycin Analogs by an Engineered Polyketide Synthase

John R. Jacobsen, C. Richard Hutchinson, David E. Cane et al. · Science · 1997 · 259 citations

Engineering, Biotechnology, Molecular Biology +17

Enantiodivergent syntheses of (+)- and (-)-nonactic acid and the total synthesis of nonactin

Paul A. Bartlett, James D. Meadows, Eckhard Ottow · Journal of the American Chemical Society · 1984 · 132 citations

Natural Sciences, Biochemistry, Chemistry +7

Synthesis of (.+-.)-nonactic acid

Manuel J. Arco, Marion Trammell, James D. White · The Journal of Organic Chemistry · 1976 · 88 citations

Natural Sciences, Biochemistry, Chemistry +6

C-O Bond Formation by Polyketide Synthases

Hyung‐Jin Kwon, Wyatt C. Smith, A. Janelle Scharon et al. · Science · 2002 · 79 citations

Engineering, Biotechnology, Molecular Biology +17

Mobile ionophores are a novel class of P‐glycoprotein inhibitors

Marie Nicole Borrel, Elene Pereira, Marina Fiallo et al. · European Journal of Biochemistry · 1994 · 78 citations

Medicine, Pharmacokinetics, Pharmacology +17