The viral tropism of two distinct oncolytic viruses, reovirus and myxoma virus, is modulated by cellular tumor suppressor gene status

An Adenovirus Mutant That Replicates Selectively in p53- Deficient Human Tumor Cells

James R. Bischoff, David H. Kirn, Angelica Williams et al. · Science · 1996 · 1.8K citations

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Integration of interferon-α/β signalling to p53 responses in tumour suppression and antiviral defence

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Reovirus Therapy of Tumors with Activated Ras Pathway

Matthew Coffey, James E. Strong, Peter Forsyth et al. · Science · 1998 · 752 citations

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The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirus

James E. Strong · The EMBO Journal · 1998 · 558 citations

Life Sciences, Molecular Biology, Oncology +14

Late viral RNA export, rather than p53 inactivation, determines ONYX-015 tumor selectivity

Clodagh C. O’Shea, Leisa Johnson, Bridget Bagus et al. · Cancer Cell · 2004 · 379 citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +14