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Design, synthesis and biological evaluations of novel 7-[3-(1-aminocycloalkyl)pyrrolidin-1-yl]-6-desfluoro-8-methoxyquinolones with potent antibacterial activity against multi-drug resistant Gram-positive bacteria

Rie N. Miyauchi, Katsuhiro Kawakami, Masao Ito, Norikazu Matsuhashi, Hitoshi Ohki, Hiroaki Inagaki, Hisashi Takahashi, Makoto Takemura

Bioorganic & Medicinal Chemistry · 2009 · 12 citations · 19 references

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19

Tables for determining the statistical significance of mutation frequencies

Marvin A. Kastenbaum, K.O. Bowman · Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis · 1970 · 973 citations

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Synthesis and Antibacterial Activity of U-100592 and U-100766, Two Oxazolidinone Antibacterial Agents for the Potential Treatment of Multidrug-Resistant Gram-Positive Bacterial Infections

Steven J. Brickner, Douglas K. Hutchinson, Michael R. Barbachyn et al. · Journal of Medicinal Chemistry · 1996 · 573 citations

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In vitro activity of Bay 09867, a new quinoline derivative, compared with those of other antimicrobial agents

R. Wise, J. M. Andrews, Laura Edwards · Antimicrobial Agents and Chemotherapy · 1983 · 480 citations · Full text

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Increasing resistance of Streptococcus pneumoniae to fluoroquinolones: results of a Hong Kong multicentre study in 2000

Pak‐Leung Ho · Journal of Antimicrobial Chemotherapy · 2001 · 231 citations · Full text

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Novel Fluoroquinolone Antibacterial Agents Containing Oxime-Substituted (Aminomethyl)pyrrolidines:  Synthesis and Antibacterial Activity of 7-(4-(Aminomethyl)-3-(methoxyimino)pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro- 4-oxo-1,4-dihydro[1,8]naphthyridine-3-carboxylic Acid (LB20304)<sup>,1</sup>

Chang Yong Hong, Young Kwan Kim, Jay Hyok Chang et al. · Journal of Medicinal Chemistry · 1997 · 127 citations

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