Inactivation of adenosine A2A receptors reverses working memory deficits at early stages of Huntington's disease models

Exon 1 of the HD Gene with an Expanded CAG Repeat Is Sufficient to Cause a Progressive Neurological Phenotype in Transgenic Mice

Laura Mangiarini, Kirupa Sathasivam, Mary J. Seller et al. · Cell · 1996 · 3.1K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Aggregation of Huntingtin in Neuronal Intranuclear Inclusions and Dystrophic Neurites in Brain

Marian DiFiglia, Ellen Sapp, Kathryn Chase et al. · Science · 1997 · 2.9K citations

Life Sciences, Neurobiology, Neuroscience +16

Dichotomous Dopaminergic Control of Striatal Synaptic Plasticity

Weixing Shen, Marc Flajolet, Paul Greengard et al. · Science · 2008 · 1.2K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Characterization of Progressive Motor Deficits in Mice Transgenic for the Human Huntington’s Disease Mutation

Rebecca J. Carter, Lisa A. Lione, Trevor Humby et al. · Journal of Neuroscience · 1999 · 959 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Postsynaptic endocannabinoid release is critical to long-term depression in the striatum

Gregory L. Gerdeman, Jennifer Ronesi, David M. Lovinger · Nature Neuroscience · 2002 · 748 citations

Life Sciences, Neurobiology, Neuroscience +13