Concepedia

Publication | Open Access

Poly(ADP-Ribose)Polymerase Inhibition Counteracts Cataract Formation and Early Retinal Changes in Streptozotocin-Diabetic Rats

DOIFull Paper Access

65

Citations

42

References

2009

Year

Viktor R. Drel, Weizheng Xu, Jie Zhang, Peter F. Kador, Tayyeba K. Ali, Jeho Shin, Ulrich Julius, Barbara S. Slusher, Azza B. El‐Remessy, Irina G. Obrosova
Investigative Ophthalmology & Visual Science

Abstract

PARP activation is implicated in the formation of diabetic cataract and in early retinal changes. These findings provide a rationale for the development of PARP inhibitors for the prevention of diabetic ocular complications.

References

YearCitations

Page 1