The Breast Cancer Resistance Protein (BCRP/ABCG2) Affects Pharmacokinetics, Hepatobiliary Excretion, and Milk Secretion of the Antibiotic Nitrofurantoin

A multidrug resistance transporter from human MCF-7 breast cancer cells

L. Austin Doyle, Weidong Yang, Lynne V. Abruzzo et al. · Proceedings of the National Academy of Sciences · 1998 · 2.3K citations

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The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria

Johan W. Jonker, Marije Buitelaar, Els Wagenaar et al. · Proceedings of the National Academy of Sciences · 2002 · 821 citations · Full text

Medicine, Oncology, Toxicology +14

Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitremorgin C.

Arnold van Loevezijn, Jeany M Lakhai, Martin van der Valk et al. · PubMed · 2002 · 687 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Role of Breast Cancer Resistance Protein in the Bioavailability and Fetal Penetration of Topotecan

Johan W. Jonker · JNCI Journal of the National Cancer Institute · 2000 · 639 citations · Full text

Medicine, Oncology, Pharmacology +17

Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA.

Raymond Evers, Marcel Kool, Liesbeth van Deemter et al. · Journal of Clinical Investigation · 1998 · 615 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17