Four Waves of Hepatocyte Proliferation Linked with Three Waves of Hepatic Fat Accumulation during Partial Hepatectomy-Induced Liver Regeneration

Abstract

PH-induced liver regeneration consists of four continuous waves of hepatocyte proliferation coupled with three waves of hepatic fat accumulation. Bmal1, Wee1, and Cdc2 may not form a pathway regulating the circadian rhythm of hepatocyte mitosis during liver regeneration.