Phosphomimetic Mutation of Cysteine String Protein-α Increases the Rate of Regulated Exocytosis by Modulating Fusion Pore Dynamics in PC12 Cells

Abstract

CSPα may modulate fusion pore dynamics in a phosphorylation-dependent manner. Therefore, through changing its phosphorylated state influenced by diverse cellular signalings, CSPα may have a great capacity to modulate the rate of regulated exocytosis.