ChemMedChem · 2009 · 62 citations · 8 references
PharmacyMedicinal ChemistryPharmacologyDrug DiscoveryStructure-activity RelationshipsSynthetic Medicinal ChemistryEnzyme InhibitionCyclooxygenase InhibitorsCyclooxygenase-1 InhibitionNonsteroidal Anti-inflammatory Drug Pharmacology
Abstract Asborin , the carbaborane analogue of aspirin, was obtained by a high‐yield synthetic procedure and proved to be an active cyclooxygenase (COX) inhibitor (H: white, B: beige, C: gray, O: blue). magnified image
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