Antiplatelet effect of sanguinarine is correlated to calcium mobilization, thromboxane and cAMP production

The aggregation of blood platelets

G. V. R. Born, Michael Cross · The Journal of Physiology · 1963 · 2.1K citations

Medicine, Cell Biology, Hematology +12

Sanguinarine (Pseudochelerythrine) Is a Potent Inhibitor of NF-κB Activation, IκBα Phosphorylation, and Degradation

Madan M. Chaturvedi, Ashok Kumar, Bryant G. Darnay et al. · Journal of Biological Chemistry · 1997 · 285 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

NAD(P)H oxidase–dependent platelet superoxide anion release increases platelet recruitment

Florian Krötz, Hae Young Sohn, Torsten Gloe et al. · Blood · 2002 · 261 citations

Life Sciences, Cell Biology, Physiology +12

Antiinflammatory Activity of Quaternary Benzophenanthridine Alkaloids from<i>Chelidonoum majus</i>*,**

J Lenfeld, M Kroutil, E. Maršálek et al. · Planta Medica · 1981 · 260 citations

Medicine, Medicinal Chemistry, Pharmacology +12

The Benzo[c]phenanthridine Alkaloid, Sanguinarine, Is a Selective, Cell-active Inhibitor of Mitogen-activated Protein Kinase Phosphatase-1

Andreas Vogt, Aletheia Tamewitz, John Skoko et al. · Journal of Biological Chemistry · 2005 · 184 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +11