O-Spiro C-aryl glucosides as novel sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors

The Relationship of Glycemic Exposure (HbA1c) to the Risk of Development and Progression of Retinopathy in the Diabetes Control and Complications Trial

Diabetes · 1995 · 1K citations

Medicine, Internal Medicine, Diabetology +16

Effect of intensive therapy on the development and progression of diabetic nephropathy in the Diabetes Control and Complications Trial

The Diabetes Control and Complications Research Group · Kidney International · 1995 · 695 citations · Full text

Medicine, Internal Medicine, Nephrology +16

Discovery of Dapagliflozin: A Potent, Selective Renal Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Inhibitor for the Treatment of Type 2 Diabetes

Wei Meng, Bruce A. Ellsworth, Alexandra A. Nirschl et al. · Journal of Medicinal Chemistry · 2008 · 628 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

The human kidney low affinity Na+/glucose cotransporter SGLT2. Delineation of the major renal reabsorptive mechanism for D-glucose.

Y. Kanai, W S Lee, Dennis Brown et al. · Journal of Clinical Investigation · 1994 · 624 citations · Full text

Life Sciences, Molecular Biology, Physiology +15

The Effect of Intensive Diabetes Therapy on the Development and Progression of Neuropathy

Annals of Internal Medicine · 1995 · 602 citations

Medicine, Internal Medicine, Neurology +17