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Novel selective human melanocortin-3 receptor ligands: Use of the 4-amino-1,2,4,5-tetrahydro-2-benzazepin-3-one (Aba) scaffold

Steven Ballet, Alexander Yur'evich Mayorov, Minying Cai, Dagmara Tymecka, Kevin Brown Chandler, Erin S. Palmer, Karolien Van Rompaey, Aleksandra Misicka, Dirk Tourwé, Victor J. Hruby

Bioorganic & Medicinal Chemistry Letters · 2007 · 31 citations · 32 references

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32

Methods for drug discovery: development of potent, selective, orally effective cholecystokinin antagonists

B. Evans, Kenneth E. Rittle, Mark G. Bock et al. · Journal of Medicinal Chemistry · 1988 · 1.4K citations · Full text

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Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass

Airu S. Chen, Donald J. Marsh, Myrna E. Trumbauer et al. · Nature Genetics · 2000 · 899 citations

, , +16

Molecular cloning, expression, and gene localization of a fourth melanocortin receptor

Ira Gantz, Hiroto Miwa, Y Konda et al. · Journal of Biological Chemistry · 1993 · 852 citations · Full text

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Chain reversals in proteins

Peter N. Lewis, Frank A. Momany, Harold A. Scheraga · Biochimica et Biophysica Acta (BBA) - Protein Structure · 1973 · 660 citations

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Cyclic lactam .alpha.-melanotropin analogs of Ac-Nle4-cyclo[Asp5,D-Phe7,Lys10]-.alpha.-melanocyte-stimulating hormone-(4-10)-NH2 with bulky aromatic amino acids at position 7 show high antagonist potency and selectivity at specific melanocortin receptors

Victor J. Hrubu, Dongsi Lu, Shubh D. Sharma et al. · Journal of Medicinal Chemistry · 1995 · 352 citations · Full text

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