Genetic polymorphisms of apolipoprotein E4 and tumor necrosis factor β as predisposing factors for increased inflammatory cytokines after cardiopulmonary bypass

Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor alpha: relevance to genetic predisposition to systemic lupus erythematosus.

Chaim O. Jacob, Zdenka Fronek, M Koo et al. · Proceedings of the National Academy of Sciences · 1990 · 632 citations

Life Sciences, Genetics, Immunology +17

A genomic polymorphism within the tumor necrosis factor locus influences plasma tumor necrosis factor-alpha concentrations and outcome of patients with severe sepsis

Frank Stüber, Frank Bokelmann, Ulrich F. Schade · Critical Care Medicine · 1996 · 552 citations

Life Sciences, Genetics, Molecular Genetics +15

Polymorphic structure of the tumor necrosis factor (TNF) locus: an NcoI polymorphism in the first intron of the human TNF-beta gene correlates with a variant amino acid in position 26 and a reduced level of TNF-beta production.

Gerald Messer, Ulrich Spengler, M. Jung et al. · The Journal of Experimental Medicine · 1991 · 548 citations · Full text

Life Sciences, Genetics, Molecular Genetics +15

Off-pump coronary artery bypass grafting decreases risk-adjusted mortality and morbidity

Joseph C. Cleveland, A. Laurie Shroyer, Anita Y. Chen et al. · The Annals of Thoracic Surgery · 2001 · 457 citations · Full text

Medicine, Cardiology, Surgery +10

Modulation of plasma triglyceride levels by apoE phenotype: a meta-analysis.

Jean Dallongeville, Suzanne Lussier‐Cacan, Jean Davignon · Journal of Lipid Research · 1992 · 451 citations · Full text

Life Sciences, Biochemistry, Cardiovascular Genetics +15