Reaching out to the lost generation of adults with early-treated phenylketonuria (PKU)

Efficacy of sapropterin dihydrochloride (tetrahydrobiopterin, 6R-BH4) for reduction of phenylalanine concentration in patients with phenylketonuria: a phase III randomised placebo-controlled study

Harvey L. Levy, Andrzej Milanowski, Anupam Chakrapani et al. · The Lancet · 2007 · 311 citations

Pharmacy, Pharmacotherapy, Clinical Nutrition +6

How practical are recommendations for dietary control in phenylketonuria?

JH Walter, F. White, SK Hall et al. · The Lancet · 2002 · 301 citations

Agriculture, Nutrition, Nutritional Sciences +8

Phenylketonuria in adulthood: A collaborative study

Richard Koch, Barbara K. Burton, George Hoganson et al. · Journal of Inherited Metabolic Disease · 2002 · 215 citations

Medicine, Endocrinology, Pediatrics +3

Efficacy of Sapropterin Dihydrochloride in Increasing Phenylalanine Tolerance in Children with Phenylketonuria: A Phase III, Randomized, Double-Blind, Placebo-Controlled Study

Friedrich K. Trefz, Barbara K. Burton, Nicola Longo et al. · The Journal of Pediatrics · 2009 · 192 citations

Pharmacy, Pediatrics, Pharmacotherapy +7

Psychiatric symptoms and disorders in phenylketonuria☆

Virdette L. Brumm, Deborah A. Bilder, Susan E. Waisbren · Molecular Genetics and Metabolism · 2009 · 158 citations

Medicine, Psychiatry, Psychology +12