Noscapine sensitizes chemoresistant ovarian cancer cells to cisplatin through inhibition of HIF-1α

Hypoxia-inducible factor-1-dependent regulation of the multidrug resistance (MDR1) gene.

Katrina M. Comerford, Timothy J. Wallace, Jörn Karhausen et al. · PubMed · 2002 · 844 citations

Medicine, Oncology, Pharmacology +16

Regulation of the Hypoxia-inducible Transcription Factor 1α by the Ubiquitin-Proteasome Pathway

Pekka Kallio, W.J. Wilson, Sallyann L. O’Brien et al. · Journal of Biological Chemistry · 1999 · 747 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF

Nicola J. Mabjeesh, Daniel Escuín, Theresa LaVallee et al. · Cancer Cell · 2003 · 726 citations

Medicine, Cancer Biology, Oncology +12

Topoisomerase I-Mediated Inhibition of Hypoxia-Inducible Factor 1

Annamaria Rapisarda, Badarch Uranchimeg, Olivier Sordet et al. · Cancer Research · 2004 · 299 citations

Medicine, Molecular Biology, Oncology +14

Geldanamycin induces degradation of hypoxia-inducible factor 1alpha protein via the proteosome pathway in prostate cancer cells.

Nicola J. Mabjeesh, Dawn E. Post, Margaret Willard et al. · PubMed · 2002 · 299 citations

Medicine, Oncology, Pharmacology +13