Synthesis of Functionalized Tetrahydro‐4‐oxoindeno[1,2‐<i>b</i>]pyrroles from Ninhydrin, Acetylenedicarboxylates, and Primary Amines

Abstract

Abstract A one‐pot synthesis of dialkyl 1,3a,4,8b‐tetrahydro‐3a,8b‐dihydroxy‐1‐alkyl‐4‐oxoindeno[1,2‐ b ]pyrrole‐2,3‐dicarboxylates via three‐component reaction from indan‐1,2,3‐trione hydrate (ninhydrin), primary amines, and dialkyl acetylenedicarboxylates is described.