A Pilot, Randomized, Placebo-Controlled, Double-Blind Phase 0/Biomarker Study on Effect of Artepillin C–Rich Extract of Brazilian Propolis in Frequent Colorectal Adenoma Polyp Patients

Abstract

The results from our pilot study did not provide evidence that Brazilian propolis was effective in preventing changes occurring during early stages of colon cancer. In contrast, propolis may have detrimental side effects on muscle tissue, including myocardial cells.