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A study to assess the effects of a broad-spectrum immune modulatory therapy on mortality and morbidity in patients with chronic heart failure: The ACCLAIM trial rationale and design

Guillermo Torre‐Amione, Robert C. Bourge, Wilson S. Colucci, Barry Greenberg, Craig M. Pratt, Jean L. Rouleau, F Sestier, Lemuel A. Moyé, John A. Geddes, Agnes Nemet,

Canadian Journal of Cardiology · 2007 · 17 citations · 23 references

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23

Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.

Valerie A. Fadok, Donna L. Bratton, Anatole Konowal et al. · Journal of Clinical Investigation · 1998 · 3.1K citations · Full text

, , +17

Elevated Circulating Levels of Tumor Necrosis Factor in Severe Chronic Heart Failure

Beth Levine, Jill Kalman, Lloyd Mayer et al. · New England Journal of Medicine · 1990 · 2.6K citations · Full text

, , +9

Randomized, Double-Blind, Placebo-Controlled, Pilot Trial of Infliximab, a Chimeric Monoclonal Antibody to Tumor Necrosis Factor-α, in Patients With Moderate-to-Severe Heart Failure

Eugene S. Chung, Milton Packer, Kim Hung Lo et al. · Circulation · 2003 · 1.6K citations

, , +12

Targeted Anticytokine Therapy in Patients With Chronic Heart Failure

Douglas L. Mann, John J.V. McMurray, Milton Packer et al. · Circulation · 2004 · 1.2K citations

, , +15

Proinflammatory cytokine levels in patients with depressed left ventricular ejection fraction: A report from the studies of left ventricular dysfunction (SOLVD)

Guillermo Torre‐Amione, Samir Kapadia, Claude R. Benedict et al. · Journal of the American College of Cardiology · 1996 · 1.2K citations

, , +12