Synthesis of <i>N</i>‐Arylamides by Copper‐Catalyzed Amination of Aryl Halides with Nitriles

Abstract

Abstract A copper‐catalyzed amination of aryl halides with nitriles has been developed. The use of nitriles as nitrogen nucleophiles can make the synthesis of N ‐arylamides more simple than that using amides through in‐situ hydrolysis. A variety of N ‐arylamides and benzoxazole derivatives can be synthesized according to this approach.