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Synthesis and antitumor evaluation of novel 5-substituted-4-hydroxy-8-nitroquinazolines as EGFR signaling-targeted inhibitors

Medicinal ChemistryEgfr Signaling-targeted InhibitorsNovel 5-Substituted-4-hydroxy-8-nitroquinazolinesPharmacologyPharmacological AgentPharmacotherapyAntitumor EvaluationAnti-cancer AgentDrug DevelopmentMedicinePharmaceutical ChemistryTumor BiologyDrug Discovery