Concepedia

Unsaturated β-ketoesters as versatile electrophiles in organocatalysis

Susy Piovesana, Daniele M. Scarpino Schietroma, Ludovico G. Tulli, Mattia R. Monaco, Marco Bella

Chemical Communications · 2010 · 24 citations · 40 references

DOI

Abstract

Beta-ketoesters, which have widely been employed as nucleophiles, are also useful electrophiles in organocatalytic quinine mediated cascade reactions, leading to the formation of products bearing multiple stereocenters in high stereoselectivity.

References

40

Catalytic Enantioselective Construction of All-Carbon Quaternary Stereocenters

Barry M. Trost, Chunhui Jiang · Synthesis · 2006 · 983 citations

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Highly Enantioselective Conjugate Addition of Nitromethane to Chalcones Using Bifunctional Cinchona Organocatalysts

Benedek Vakulya, Szilárd Varga, Tibor Soós · Organic Letters · 2005 · 976 citations

Control of four stereocentres in a triple cascade organocatalytic reaction

Dieter Enders, Matthias R. M. Hüttl, Christoph Grondal et al. · Nature · 2006 · 904 citations

, , +9

Highly Enantioselective Conjugate Addition of Nitromethane to Chalcones Using Bifunctional Cinchona Organocatalysts.

Benedek Vakulya, Szilárd Varga, Antal Csámpai et al. · ChemInform · 2005 · 816 citations · Full text

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Enantioselective Organo-Cascade Catalysis

Yong Huang, Abbas M. Walji, Catharine H. Larsen et al. · Journal of the American Chemical Society · 2005 · 730 citations

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