The autolysin of<i>Porphyromonas gingivalis</i>is involved in outer membrane vesicle release

Abstract

An autolysin mutant of Porphyromonas gingivalis was constructed and its outer membrane vesicle production was compared to that of wild-type strain 381. The autolysin mutant produced elevated levels of vesicles relative to the parental strain. It is suggested that vesicle formation of this organism may be regulated by cell wall turnover.