Chromosome 9p21 Loss and p16 Inactivation in Primary Sclerosing Cholangitis-Associated Cholangiocarcinoma

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

James G. Herman, Jeremy R. Graff, Sanna Myöhänen et al. · Proceedings of the National Academy of Sciences · 1996 · 5.7K citations

Life Sciences, Genetics, Molecular Biology +17

Natural history and prognostic factors in 305 Swedish patients with primary sclerosing cholangitis.

Ulrika Broomé, Rolf Olsson, Lars Lööf et al. · Gut · 1996 · 822 citations · Full text

Medicine, Internal Medicine, Pathology +15

Purification of DNA from formaldehyde fixed and paraffin embedded human tissue

Susan Goelz, Stanley R. Hamilton, Bert Vogelstein · Biochemical and Biophysical Research Communications · 1985 · 811 citations

Medicine, Molecular Biology, Pathology +9

Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas.

Mieke Schutte, Ralph H. Hruban, Joseph Geradts et al. · PubMed · 1997 · 665 citations

Medicine, Genetics, Oncology +17

Frequency of homozygous deletion at p16/CDKN2 in primary human tumours

Paul Cairns, Thomas J. Polascik, Yolanda Eby et al. · Nature Genetics · 1995 · 646 citations

Medicine, Molecular Genetics, Oncology +14