Concepedia

Vitiligo autoantibodies are effective against melanoma

Pnina Fishman, R. Zigelman, Suzi Floro, Meir Djaldetti, Esther Azizi, Yehuda Shoenfeld, Benjamin Sredni, Galit Yecheskel, Soldano Ferrone, Samario Chaitchik

Cancer · 1993 · 63 citations · 23 references

DOI

Abstract

The results of this study point to the presence of anti-melanoma autoantibodies in the sera of patients with localized and diffuse vitiligo. These antibodies have a destructive effect on melanoma cells in vitro and in vivo.

References

23

Antibodies to normal human melanocytes in vitiligo.

Gail K. Naughton, Magdalena Eisinger, J C Bystryn · The Journal of Experimental Medicine · 1983 · 217 citations · Full text

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Evidence for Immunologic Mechanisms in Human Vitiligo: Patients' Sera Induce Damage to Human Melanocytes In Vitro by Complement-Mediated Damage and Antibody-Dependent Cellular Cytotoxicity

David A. Norris, R Mark. Kissinger, Gail M. Naughton et al. · Journal of Investigative Dermatology · 1988 · 206 citations

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Autoimmune Vitiligo

Kenneth C. Hertz, Laura A. Gazze, Charles H. Kirkpatrick et al. · New England Journal of Medicine · 1977 · 189 citations

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Prognostic significance of hypopigmentation in malignant melanoma

J.‐C. Bystryn · Archives of Dermatology · 1987 · 176 citations

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Relation Between the Incidence and Level of Pigment Cell Antibodies and Disease Activity in Vitiligo

Ronald Harning, Jian Cui, Jean‐Claude Bystryn · Journal of Investigative Dermatology · 1991 · 173 citations

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