Development of potent, orally active 1-substituted-3,4-dihydro-2-quinolone glycogen phosphorylase inhibitors

A new allosteric site in glycogen phosphorylase b as a target for drug interactions

Nikos G. Oikonomakos, Katerina E. Tsitsanou, Nikos G. Gavalas et al. · Structure · 2000 · 132 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Human liver glycogen phosphorylase inhibitors bind at a new allosteric site

Virginia L. Rath, Mark Ammirati, Dennis E. Danley et al. · Chemistry & Biology · 2000 · 126 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +14

Ready Access to Fluorinated Phosphonate Mimics of Secondary Phosphates. Synthesis of the (α,α-Difluoroalkyl)phosphonate Analogues of <scp>l</scp>-Phosphoserine, <scp>l</scp>-Phosphoallothreonine, and <scp>l</scp>-Phosphothreonine

David B. Berkowitz, MariJean Eggen, Quanrong Shen et al. · The Journal of Organic Chemistry · 1996 · 125 citations

Natural Sciences, Biochemistry, Chemistry +7

Activation of Human Liver Glycogen Phosphorylase by Alteration of the Secondary Structure and Packing of the Catalytic Core

Virginia L. Rath, Mark Ammirati, Peter K. LeMotte et al. · Molecular Cell · 2000 · 98 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

An Electrophilic Aromatic Substitution by <i>N</i>-Methoxyamides <i>via</i> Hypervalent Iodine Intermediates

Yasuo Kikugawa, Masami Kawase · Chemistry Letters · 1990 · 87 citations

Natural Sciences, Chemistry, Organic Chemistry +10