Concepedia

Lipophilic β-adrenoceptor antagonists and local anesthetics are effective direct activators of g-proteins

A Hagelüken, Lore Grünbaum, Bernd Nürnberg, Rainer Harhammer, Walter Schunack, Roland Seifert

Biochemical Pharmacology · 1994 · 99 citations · 16 references

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References

16

Mastoparan, a peptide toxin from wasp venom, mimics receptors by activating GTP-binding regulatory proteins (G proteins).

Tsutomu Higashijima, Sonoko Uzu, Terumi Nakajima et al. · Journal of Biological Chemistry · 1988 · 679 citations · Full text

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Regulation of Gi and Go by mastoparan, related amphiphilic peptides, and hydrophobic amines. Mechanism and structural determinants of activity.

Tsutomu Higashijima, John P. Burnier, Elliott M. Ross · Journal of Biological Chemistry · 1990 · 602 citations · Full text

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Interaction of substance P, compound 4880 and mastoparan with the α-subunit C-terminus of G protein

Marc Mousli, Christian Bronner, Joël Bockaert et al. · Immunology Letters · 1990 · 179 citations

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II. Erythrocyte membrane stabilization by local anesthetics and tranquilizers

Philip Seeman · Biochemical Pharmacology · 1966 · 130 citations

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Involvement of pertussis toxin-sensitive G-proteins in the hormonal inhibition of dihydropyridine-sensitive Ca2+ currents in an insulin-secreting cell line (RINm5F).

Andrej Schmidt, J. Hescheler, Stefan Offermanns et al. · Journal of Biological Chemistry · 1991 · 93 citations · Full text

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