In vitro selection of DNA aptamers that bind l-tyrosinamide

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

Julie Thompson, Desmond G. Higgins, Toby J. Gibson · Nucleic Acids Research · 1994 · 64.9K citations · Full text

Life Sciences, Bioinformatics, Sequence Analysis +14

Type II DNA topoisomerases: Enzymes that can unknot a topologically knotted DNA molecule via a reversible double-strand break

Leroy F. Liu, Chen Liu, Bruce Alberts · Cell · 1980 · 546 citations

Life Sciences, Biochemistry, Molecular Biology +14

Quadruplex structure of Oxytricha telomeric DNA oligonucleotides

Flint W. Smith, Juli Feigon · Nature · 1992 · 522 citations

Life Sciences, Genetics, Molecular Biology +14

A Sign Inversion Mechanism for Enzymatic Supercoiling of DNA

Patrick O. Brown, Nicholas R. Cozzarelli · Science · 1979 · 329 citations

Life Sciences, Biochemistry, Molecular Biology +8

Dual modes of death induced by etoposide in human epithelial tumor cells allow Bcl-2 to inhibit apoptosis without affecting clonogenic survival.

Richard B. Lock, Lolita Stribinskiene · PubMed · 1996 · 205 citations

Medicine, Oncology, Pharmacology +17