Synthesis of (+)-(1S,2R) and (−)-(1R,2S)-2-aminocyclobutane-1-carboxylic acids

Residue-based control of helix shape in β-peptide oligomers

Daniel H. Appella, Laurie A. Christianson, Daniel A. Klein et al. · Nature · 1997 · 622 citations

Life Sciences, Biochemistry, Molecular Biology +15

Stereoselective Intermolecular [2 + 2]-Photocycloaddition Reactions and Their Application in Synthesis

Thorsten Bach · Synthesis · 1998 · 297 citations

Natural Sciences, Chemistry, Organic Chemistry +13

Structure−Activity Studies of 14-Helical Antimicrobial β-Peptides:  Probing the Relationship between Conformational Stability and Antimicrobial Potency

Tami L. Raguse, Emilie A. Porter, Bernard Weisblum et al. · Journal of the American Chemical Society · 2002 · 283 citations

Life Sciences, Biochemistry, Microbiology +17

Synthesis and Structural Characterization of Helix-Forming β-Peptides:  <i>trans</i>-2-Aminocyclopentanecarboxylic Acid Oligomers

Daniel H. Appella, Laurie A. Christianson, Daniel A. Klein et al. · Journal of the American Chemical Society · 1999 · 214 citations

Life Sciences, Biochemistry, Molecular Biology +17

Surprisingly Stable Helical Conformations in α/β‐Peptides by Incorporation of <i>cis</i>‐β‐Aminocyclopropane Carboxylic Acids

Silvia De Pol, Chiara Zorn, Christian D. Klein et al. · Angewandte Chemie International Edition · 2004 · 211 citations

Life Sciences, Biochemistry, Biophysics +13