HLA-DR typing using DNA amplification by the polymerase chain reaction and sequential hybridization to sequence-specific oligonucleotide probes

DNA sequencing with chain-terminating inhibitors

Frederick Sanger, S. Nicklen, Alan Coulson · Proceedings of the National Academy of Sciences · 1977 · 69.3K citations · Full text

Life Sciences, Microbiology, Molecular Biology +10

HLA-DQβ gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

John A. Todd, John I. Bell, Hugh O. McDevitt · Nature · 1987 · 2K citations

Medicine, Genetics, Molecular Genetics +9

Analysis of enzymatically amplified β-globin and HLA-DQα DNA with allele-specific oligonucleotide probes

Randall K. Saiki, Teodorica L. Bugawan, Glenn T. Horn et al. · Nature · 1986 · 1.8K citations

Life Sciences, Genetics, Molecular Genetics +14

Detection of sickle cell beta S-globin allele by hybridization with synthetic oligonucleotides.

Brenda J. Conner, Antonio A. Reyes, C Morin et al. · Proceedings of the National Academy of Sciences · 1983 · 533 citations · Full text

Medicine, Genetics, Molecular Genetics +15

Allelic sequence variation of the HLA-DQ loci: relationship to serology and to insulin-dependent diabetes susceptibility.

Glenn T. Horn, Teodorica L. Bugawan, Christopher M. Long et al. · Proceedings of the National Academy of Sciences · 1988 · 376 citations · Full text

Life Sciences, Genetics, Immunology +17