Recombinant hirudin treatment modulates aquaporin-4 and aquaporin-9 expression after intracerebral hemorrhage in vivo

Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke

Geoffrey T. Manley, Miki Fujimura, Tonghui Ma et al. · Nature Medicine · 2000 · 1.5K citations

Medicine, Neurology, Neuroscience +17

Specialized Membrane Domains for Water Transport in Glial Cells: High-Resolution Immunogold Cytochemistry of Aquaporin-4 in Rat Brain

Søren Nielsen, Erlend A. Nagelhus, Mahmood Amiry‐Moghaddam et al. · Journal of Neuroscience · 1997 · 1.4K citations · Full text

Life Sciences, Neurobiology, Neuroscience +14

Aquaporin‐4 facilitates reabsorption of excess fluid in vasogenic brain edema

Marios C. Papadopoulos, Geoffrey T. Manley, Sanjeev Krishna et al. · The FASEB Journal · 2004 · 758 citations

Medicine, Neurology, Neuroscience +17

Effect of brain edema on infarct volume in a focal cerebral ischemia model in rats.

Teng‐Nan Lin, Yang He, Gang Wu et al. · Stroke · 1993 · 722 citations · Full text

Medicine, Neurobiology, Neuroscience +14

Molecular characterization of an aquaporin cDNA from brain: candidate osmoreceptor and regulator of water balance.

Jin Sup Jung, Ratan V. Bhat, Gregory M. Preston et al. · Proceedings of the National Academy of Sciences · 1994 · 720 citations

Life Sciences, Molecular Biology, Neuroscience +14