Concepedia

Targeted Radiosensitization by the Chk1 Inhibitor SAR-020106

Gerben R. Borst, Martin McLaughlin, Joan Kyula, Sari Neijenhuis, Aadil Khan, James Good, Shane Zaidi, Ned Powell, Pascal Meier, Ian Collins,

International Journal of Radiation Oncology*Biology*Physics · 2012 · 55 citations · 12 references

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Surfing the p53 network

Bert Vogelstein, David P. Lane, Arnold J. Levine · Nature · 2000 · 6.6K citations

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Visualizing Spatiotemporal Dynamics of Multicellular Cell-Cycle Progression

Asako Sakaue-Sawano, Hiroshi Kurokawa, Toshifumi Morimura et al. · Cell · 2008 · 2.3K citations · Full text

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Mechanism of Radiosensitization by the Chk1/2 Inhibitor AZD7762 Involves Abrogation of the G2 Checkpoint and Inhibition of Homologous Recombinational DNA Repair

Meredith A. Morgan, Leslie A. Parsels, Lili Zhao et al. · Cancer Research · 2010 · 299 citations · Full text

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The ATM Inhibitor KU-55933 Suppresses Cell Proliferation and Induces Apoptosis by Blocking Akt In Cancer Cells with Overactivated Akt

Yan Li, Da-Qing Yang · Molecular Cancer Therapeutics · 2010 · 117 citations

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The Preclinical Pharmacology and Therapeutic Activity of the Novel CHK1 Inhibitor SAR-020106

Michael I. Walton, Paul D. Eve, Angela Hayes et al. · Molecular Cancer Therapeutics · 2010 · 101 citations · Full text

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