Concepedia

Ethyl acetate extract of Patrinia scabiosaefolia downregulates anti-apoptotic Bcl-2/Bcl-XL expression, and induces apoptosis in human breast carcinoma MCF-7 cells independent of caspase-9 activation

Lawrence C.M. Chiu, Tik-Shun Ho, Elaine Yue Ling Wong, Vincent E. C. Ooi

Journal of Ethnopharmacology · 2005 · 62 citations · 16 references

DOI

Concepts

References

16

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death

Zoltán N. Oltval, Curt Milliman, Stanley J. Korsmeyer · Cell · 1993 · 6K citations

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Bad, a heterodimeric partner for Bcl-xL and Bcl-2, displaces bax and promotes cell death

Elizabeth Yang, Jiping Zha, Jennifer Jockel et al. · Cell · 1995 · 2.1K citations · Full text

, , +7

Bax and Adenine Nucleotide Translocator Cooperate in the Mitochondrial Control of Apoptosis

Isabel Marzo, Catherine Brenner, Naoufal Zamzami et al. · Science · 1998 · 1.2K citations

, , +17

Cytometry in cell necrobiology: Analysis of apoptosis and accidental cell death (necrosis)

Zbigniew Darżynkiewicz, Gloria Juan, Xun Li et al. · Cytometry · 1997 · 1.1K citations

, , +13

Caspase-9 and APAF-1 form an active holoenzyme

Joe Rodriguez, Yuri Lazebnik · Genes & Development · 1999 · 564 citations · Full text

, , +11